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Evidence informing the UK’s COVID-19 public health response must be clear. In distinction to the serum, plasma and blood samples used for serological detection, the samples used for antigen detection are pharyngeal and nasopharyngeal swabs, which have to be handled with protein extraction liquor provided within the kits prior to detection. The primary benefit of automated CLIA analysers over rapid LFIA exams is the very excessive throughput of samples.